Micro-Coaxial Slot Antenna to Treat Bone Tumors by Thermal Ablation: Theoretical and Experimental Evaluation

Authors

  • Citlalli Jessica Trujillo Romero National Institute of Rehabilitation
  • Genaro Rico Martínez National Institute of Rehabilitation
  • Lorenzo Leija Salas Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
  • Arturo Vera Hernández Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
  • Josefina Gutierrez Martínez National Institute of Rehabilitation

Keywords:

blood perfusion, bone tumors, finite element models, microwave thermal ablation, slot antenna.

Abstract

According to the American Cancer Society the number of patients with bone tumors is growing up. The extremities of the long bones are the most affected by this disease. The common treatments are surgery (amputation), radio and chemotherapy. However, their high cost and side-effects show the necessity of new treatments. These should not only eradicate the tumor but also offer a major control over the treated area. In this sense, the microwave ablation plays an important role. A micro-coaxial slot antenna to generated thermal ablation in bone tumors is proposed. The antenna was modeled, constructed and evaluated in pig tissue. A parametric study to evaluate the effect of the blood perfusion in the thermal distributions was done. Values of bone blood perfusion among 30-1171 ml/min/kg were included in this study. Subsequently, temperature profiles and thermal distributions generated in pig bones were obtained and compared with those obtained in the model. This evaluation shows a high level of concordance; in the best cases, a difference between simulation and measurement of 0.13°C-3.83°C and 0.08°C-0.41°C was found. This study corroborates the efficiency of the models to predict the antenna behavior and the efficiency of the proposed antenna to generated thermal ablation in bone tissue.

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Author Biographies

Citlalli Jessica Trujillo Romero, National Institute of Rehabilitation

Citlalli J. Trujillo Romero was born in Mexico City in 1983. She received the Engineer in Bionic degree from the National Polytechnic Institute, Mexico (IPN) in 2006 and the Ph.D. degree in bioelectronics, from the CINVESTAV-IPN in 2012 (Mexico City).

From 2012-2014 she worked as a post doctor at the hyperthermia unit of the oncological radiation department at the Erasmus-MC Daniel den Hoed in Rotterdam, Netherlands. She worked as a full-time professor at the National Polytechnic Institute, México (IPN) in 2015. Currently, Dr. Trujillo works as a researcher in medical sciences at the National Instituto of Rehabilitation in Mexico City. She is a part time professor at the ITESM-Mexico City since 2015. Dr. Trujillo main field of study is the use of EM fields and MW to generate thermal therapies, as well as the development of biological models by the finite element method.

Genaro Rico Martínez, National Institute of Rehabilitation

Genaro Rico Martínez was born in Veracruz- México in 1953. He received the surgeon degree in Mexico City from the National Polytechnic Institute (IPN) in 1978.  He got a recertification by the Mexican Council of Orthopedics and Traumatology in 2018.

He is a traumatology and orthopedics specialist at the National Institute of Rehabilitation in Mexico City since 1990. He works as a professor at the National Polytechnic Institute (IPN), teaching Orthopedics and Musculoskeletal Tumors. His mail field of study is the application of thermal therapies to treat bone tumors

Lorenzo Leija Salas, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional

Lorenzo Leija Salas was born in San Luis Potosi-Mexico in 1953.  He received his M.Sc. in Bioelectronics by CINVESTAV-Mexico in 1981 and the Ph.D. degree from the Universite de Nancy I, France in 1989.

He has been a researcher in the Bioelectronics Section of the Electrical Engineering Department at CINVESTAV in Mexico City per more than 30 years. His research interests include biomedical instrumentation, medical and biological use of the electromagnetic and ultrasonic radiations.

Dr. Leija is member of the National System of Researchers in Mexico, the American Institute of Ultrasound in Medicine and the Mexican Academy of Science.

Arturo Vera Hernández, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional

Arturo Vera Hernandez was born Mexico City in 1969. He received his M.Sc. in Bioelectronics by CINVESTAV-Mexico in 1995. He received the Ph.D. degree from Institute National Polytechnique de Lorraine-INPL-Nancy, France in 1999. He is a researcher in the Bioelectronics Section of the Electrical Engineering Department at CINVESTAV in Mexico City since 1999. His research interests include biomedical instrumentation, medical and biological use of the electromagnetic and ultrasonic radiations. Dr. Vera is member of the National System of Researchers in Mexico.

Josefina Gutierrez Martínez, National Institute of Rehabilitation

Josefina Gutierrez Martínez was born in Michoacan-Mexico in 1959, she received the M.Sc. degree in bioelectronics from CINVESTAV in Mexico City in 19992 and the Ph.D. degree in engineering from the National Autonomous University of Mexico in 2002. 

She is the head of the Division of research in medical engineering at the National Institute of Rehabilitation in Mexico City since 2015. She started to work at the National Institute of Rehabilitation in 2000, as a vice principal of the Biomedical Engineering department. She created the Sub direction for Technological Research in the same Instituto, in order to develop research and technological innovation projects. Her research field is technology for neurorehabilitation, devices to prevent the disability and medical information systems. Dr. Gutierrez is member of the National System of Researchers in Mexico and the Mexican Academy of Engineering.

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Published

2019-06-04

How to Cite

Trujillo Romero, C. J., Rico Martínez, G., Leija Salas, L., Vera Hernández, A., & Gutierrez Martínez, J. (2019). Micro-Coaxial Slot Antenna to Treat Bone Tumors by Thermal Ablation: Theoretical and Experimental Evaluation. IEEE Latin America Transactions, 16(11), 2731–2737. Retrieved from https://latamt.ieeer9.org/index.php/transactions/article/view/627