Open-loop dynamic optimization for nonlinear multi-input systems

Authors

Keywords:

Bioreactors, Nonlinear system, Fourier series, Trajectory optimization, bioreactors, Nonlinear System, Fourier Series, trajectory optimization

Abstract

This paper proposes a novel strategy for dynamic open-loop optimization of multivariable nonlinear systems. The methodology is based on the Fourier series and orthonormal polynomials for the control vector parameterization in a sequential direct solution approach. The advantages of this technique are that a few number of parameters is required for optimization and a smooth control profile is obtained.  The proposed strategy is evaluated in the case study of recombinant protein production, which is a nonlinear system with two control actions, the substrate, and inhibitor feed flow rate. The algorithms are tested through simulations and the results are compared with those published in the bibliography.

Published

2020-09-25
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