A Decentralized Learning Architecture for Medical Prescription Anomaly Detection via Hybrid Federated-Swarm Learning

Authors

Keywords:

Blockchains, Decentralized applications, Federated learning, InterPlanetary File System (IPFS), Medical information systems, Smart contracts

Abstract

The increasing use of electronic medical records (EMRs) has improved efficiency, accuracy, and accessibility of patient data. However, conventional centralized architectures suffer from single points of failure and data privacy issues. To address these challenges, this study proposes a decentralized machine learning architecture that combines concepts from Federated Learning (FL) and Swarm Learning (SL) for anomaly detection in medical prescriptions. The proposed architecture leverages blockchain and the InterPlanetary File System (IPFS) to enable secure model sharing and decentralized storage, thereby reducing communication complexity and establishing a transparent, decentralized parameter repository. Experimental evaluations were conducted using logistic regression (LR), a multi-layer perceptron (MLP), and a decision tree (DT) model. Compared with the FL baseline, the proposed system achieved superior efficiency, lower resource consumption, and improved latency, along with smaller block sizes. It, however, exhibited slightly lower transaction throughput and longer training rounds, reflecting the added complexity of decentralization. In predictive performance on the anomaly classification task, DT achieved the highest precision and recall under the evaluated dataset (F1-score=0.9912), followed by MLP (0.5504) and LR (0.2442). The decentralized training approach led to negligible performance loss relative to centralized models, less than 4% for LR and below 1% for both MLP and DT. Overall, the proposed system demonstrates a robust and efficient alternative for decentralized learning in healthcare applications, maintaining strong predictive performance while enhancing architectural transparency.

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Author Biographies

Ravelly Zanatta, University of Sao Paulo

Ravelly C. Zanatta is a M.Sc. student at the Institute of Mathematical and Computer Sciences of the University of Sao Paulo (ICMC-USP). He received his B.S. degree in Applied and Computational Mathematics from the State University of Central-West (UNICENTRO), in Guarapuava, PR, Brazil, in 2019. His research interests include computer networks, blockchain, machine learning, and data science.

Vinícius Vanzin, University of Sao Paulo

Vinícius J. B. Vanzin received the B.S. degree in computer engineering from UNIFTEC, Caxias do Sul, RS, Brazil in 2018. He is currently pursuing the Ph.D. degree in computer science at University of Sao Paulo, Sao Carlos, SP, Brazil. His research interests include machine learning applied to the biomedical sciences, entity normalization and structuring, interoperability of healthcare information, natural language processing, and large language models.

Saulo Matos, University of Sao Paulo

Saulo N. Matos is a Ph.D. student at the Institute of Mathematical and Computer Sciences of the University of Sao Paulo (ICMC-USP), with research focused on Machine Learning, Instrumentation, and Internet of Things. He holds a master's degree in Instrumentation, Control, and Automation of Mining Processes from the University of Ouro Preto and the Vale Technological Institute (2022). He graduated in Control and Automation Engineering from the Federal University of Ouro Preto (2020). He has published papers and patents on instrumentation, embedded systems, machine learning, and control theory.

Rodrigo Garcia, University of São Paulo

Rodrigo D. Garcia is a Ph.D. candidate at the Institute of Mathematical and Computer Sciences of the University of Sao Paulo (ICMC-USP), where he also received his M.Sc. He is currently working as a research visitor at the University of Southern California (USC). His research interests include privacy-preserving protocols and blockchain applications.

Dilvan Moreira, University of Sao Paulo

Dilvan A. Moreira received the Ph.D. degree in electronics engineering from the University of Kent at Canterbury, UK., in 1995. He conducted postdoctoral research in biomedical informatics with Stanford University, in 2008. He is currently an Associate Professor at the University of Sao Paulo (USP), Brazil. His research interests include biomedical informatics, microelectronics, and data science applications in healthcare.

Jó Ueyama, University of Sao Paulo

Jó Ueyama is a Full Professor at the Institute of Mathematical and Computer Sciences (ICMC) of the University of Sao Paulo (USP). He has been a Brazilian Research Council (CNPq) fellow since 2014. He received his Ph.D. in computer science from the University of Lancaster in 2006 and was a research fellow at the University of Kent at Canterbury before joining USP. Jó has a publication record with 72 journal articles and over 100 conference papers. His research interests are focused on computer networks, security, and blockchain.

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Published

2026-07-14

How to Cite

Zanatta, R., Vanzin, V., Matos, S., Garcia, R., Moreira, D., & Ueyama, J. (2026). A Decentralized Learning Architecture for Medical Prescription Anomaly Detection via Hybrid Federated-Swarm Learning. IEEE Latin America Transactions, 24(9), 893–904. Retrieved from https://latamt.ieeer9.org/index.php/transactions/article/view/10586